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AmberliteeIRA-402 (OH) Ion Exchange Resin Mediated Synthesis of Indolizines, Pyrrolo [1,2-a] Quinolines and Isoquinolines: Antibacterial and Antifungal evaluation of the products

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Title AmberliteeIRA-402 (OH) Ion Exchange Resin Mediated Synthesis of Indolizines,
Pyrrolo [1,2-a] Quinolines and Isoquinolines: Antibacterial and Antifungal
evaluation of the products
 
Creator Hazra, Abhijit
Mondal, Shyamal
Maity, Arindam
Naskar, Subhendu
Saha, Pritam
Paira, Rupankar
Sahu, Krishnendu B
Paira, Priyankar
Ghosh, Soma
Sinha, Chandrima
Samanta, Amalesh
Banerjee, Sukdeb
Mondal, Nirup B
 
Subject Chemistry
 
Description A number of indolizines and pyrrolo[1,2-a]quinolines/isoquinolines were prepared from phenacyl pyridinium,
quinolinium and isoquinolinium salts derived fromthe reaction of the heterocycles with
2-bromo acetophenone with alkynes and alkenes using amberliteeIRA-402 (OH) ion exchange resin as
the base. Antibacterial and antifungal studies were carried out against thirteen bacterial and four fungal
strains, which revealed that three derivatives (4a, 4b, 7a) out of fifteen are effective against all the
thirteen strains and one derivative, 10, showed dual antibactericidal and antifungal efficacy
 
Publisher Elsevier
 
Date 2011
 
Type Article
PeerReviewed
 
Relation http://dx.doi.org/10.1016/j.ejmech.2011.02.066
http://www.eprints.iicb.res.in/1256/
 
Identifier Hazra, Abhijit and Mondal, Shyamal and Maity, Arindam and Naskar, Subhendu and Saha, Pritam and Paira, Rupankar and Sahu, Krishnendu B and Paira, Priyankar and Ghosh, Soma and Sinha, Chandrima and Samanta, Amalesh and Banerjee, Sukdeb and Mondal, Nirup B (2011) AmberliteeIRA-402 (OH) Ion Exchange Resin Mediated Synthesis of Indolizines, Pyrrolo [1,2-a] Quinolines and Isoquinolines: Antibacterial and Antifungal evaluation of the products. European Journal of Medicinal Chemistry, 46 (6). pp. 2132-2140.