ICAR Research Data Repository for Knowledge Management
Synthesis and Bioevaluation of Anilido Quinolines and Fused Quinolines
EPrints@IICB
View Archive Info| Field | Value | |
| Title |
Synthesis and Bioevaluation of Anilido Quinolines and Fused Quinolines |
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| Creator |
Paira, Priyankar
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| Subject |
Chemistry
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| Description |
The quinolones anti-infactive agents are of wholly synthetic origin and are not modeled knowingly after any natural antibiotic. Several ring systems are or have been involved. Of all the totally synthetic antimicrobial agents, the fused and nonfused fluoro quinolones have proven to be the most successful economically and clinically. They are orally and parenterally active, have a broad antimicrobial spectrum that includes many frequently encountered pathogens, are bactericidial in clinically achievable doses, posses a fascinating molecular mode of action, are comparatively easily synthesized and with a few notable exceptions are safe. That is not to say that they are perfect drugs and cannot be improved but rather that they are important weapons in the ongoing struggle against morbidity and mortility caused by microbial pathogens. |
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| Date |
2009
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| Type |
Thesis
NonPeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1297/1/priyankar.pdf
Paira, Priyankar (2009) Synthesis and Bioevaluation of Anilido Quinolines and Fused Quinolines. PhD thesis, Jadavpur University. |
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| Relation |
http://www.eprints.iicb.res.in/1297/
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