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Study on Changes in the Membrane Properties of Leishmania Infected Macrophages and Their Impact on Antigen Presentation

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Title Study on Changes in the Membrane Properties of Leishmania
Infected Macrophages and Their Impact on Antigen Presentation
 
Creator Dhar, Ranjan
 
Subject Infectious Diseases and Immunology
 
Description Leishmaniasis has a long history dating back as far as the first century AD. As early as
this period, pre-Incan pottery from Ecuador and Peru displayed depictions of skin
lesions and facial deformities that are typical of cutaneous and mucocutaneous
leishmaniasis. Incan text from the 15th and 16th century and accounts from Spanish
conquistadors noted the presence of skin lesions on agricultural workers returning
from the Andes. These ulcers resembled leprosy lesions and were labeled, "white
leprosy," "Andean sickness," or "valley sickness." In Africa and India, reports in the mid-18 th century describe the disease now known as visceral leishmaniasis, as "kalazar" or "black fever." In 1756, Alexander Russell made an important advance in the discovery of Leishmaniasis after examining a Turkish patient. According to Russell,
"After it is cicatrized, it leaves an ugly scar, which remains through life, and for many months has a livid colour. When they are not irritated, they seldom give much pain."
 
Date 2012
 
Type Thesis
NonPeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1326/1/THESIS_FINAL.pdf
Dhar, Ranjan (2012) Study on Changes in the Membrane Properties of Leishmania Infected Macrophages and Their Impact on Antigen Presentation. PhD thesis, Jadavpur University.
 
Relation http://www.eprints.iicb.res.in/1326/