Record Details

Comparison of health effects between individuals with and without skin lesions in the population exposed to arsenic through drinking water in West Bengal, India

EPrints@IICB

View Archive Info
 
 
Field Value
 
Title Comparison of health effects between individuals with and without skin
lesions in the population exposed to arsenic through drinking water in West
Bengal, India
 
Creator Ghosh, Pritha
Banerjee, Mayukh
De Chaudhuri, Sujata
Choudhury, Rajdeep
Das, Jayanta K
Mukherjee, Angshuman
Sarkar, Ajoy K
Mondal, Lakshmikanta
Baidya, Kalipada
Sau, Tanmoy Jyoti
Banerjee, Apurba
Basu, Arindam
Chaudhuri, Keya
Ray, Kunal
Giri, Ashok K
 
Subject Molecular & Human Genetics
 
Description A study was conducted to explore the effect of arsenic causing conjunctivitis, neuropathy and respiratory illness in individuals, with or without skin
lesions, as a result of exposure through drinking water, contaminated with arsenic to similar extent. Exposed study population belongs to the districts of
North 24 Parganas and Nadia, West Bengal, India. A total of 725 exposed (373 with skin lesions and 352 without skin lesions) and 389 unexposed
individuals were recruited as study participants. Participants were clinically examined and interviewed. Arsenic content in drinking water, urine, nail and
hair was estimated. Individuals with skin lesion showed significant retention of arsenic in nail and hair and lower amount of urinary arsenic compared to
the group without any skin lesion. Individuals with skin lesion also showed higher risk for conjunctivitis ((odd’s ratio) OR: 7.33, 95% CI: 5.05–10.59),
peripheral neuropathy (OR: 3.95, 95% CI: 2.61–5.93) and respiratory illness (OR: 4.86, 95% CI: 3.16–7.48) compared to the group without any skin
lesion. The trend test for OR of the three diseases in three groups was found to be statistically significant. Again, individuals without skin lesion in the
exposed group showed higher risk for conjunctivitis (OR: 4.66, 95% CI: 2.45–8.85), neuropathy (OR: 3.99, 95% CI: 1.95–8.09), and respiratory illness
(OR: 3.21, 95% CI: 1.65–6.26) when compared to arsenic unexposed individuals. Although individuals with skin lesions were more susceptible to arsenicinduced
toxicity, individuals without skin lesions were also subclinically affected and are also susceptible to arsenic-induced toxicity and carcinogenicity
when compared to individuals not exposed to arsenic.
 
Date 2007
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1415/1/JOURNAL_OF_EXPOSURE_SCIENCE_AND_ENVIRONMENTAL_EPIDEMIOLOGY_17(_3)215%2D223;2007[95].pdf
Ghosh, Pritha and Banerjee, Mayukh and De Chaudhuri, Sujata and Choudhury, Rajdeep and Das, Jayanta K and Mukherjee, Angshuman and Sarkar, Ajoy K and Mondal, Lakshmikanta and Baidya, Kalipada and Sau, Tanmoy Jyoti and Banerjee, Apurba and Basu, Arindam and Chaudhuri, Keya and Ray, Kunal and Giri, Ashok K (2007) Comparison of health effects between individuals with and without skin lesions in the population exposed to arsenic through drinking water in West Bengal, India. Journal of Exposure Science and Environmental Epidemiology, 17 (3). pp. 215-223.
 
Relation http://dx.doi.org/
http://www.eprints.iicb.res.in/1415/