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Interconnection of Salt-induced Hydrophobic Compaction and Secondary Structure Formation Depends on Solution Conditions

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Field Value
 
Title Interconnection of Salt-induced Hydrophobic Compaction
and Secondary Structure Formation Depends on Solution
Conditions
 
Creator Haldar, Shubhasis
Chattopadhyay, Krishnananda
 
Subject Structural Biology & Bioinformatics
 
Description Early events of protein folding are difficult to follow.
The unfolded state may have extended and compact conformers, which interconvert at early microsecond.
Hydrophobic compaction and secondary structure formation do not occur simultaneously in aqueous solution.
They occur simultaneously in the presence of urea.
Hydrophobic collapse has been monitored at single molecular resolution
 
Publisher American Society for Biochemistry and Molecular Biology
 
Date 2012
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1519/1/JOURNAL_OF_BIOLOGICAL_CHEMISTRY_287(_14)11546%2D11555;2012[36].pdf
Haldar, Shubhasis and Chattopadhyay, Krishnananda (2012) Interconnection of Salt-induced Hydrophobic Compaction and Secondary Structure Formation Depends on Solution Conditions. The Journal of Biological Chemistry, 287 (14). pp. 11546-11555.
 
Relation http://dx.doi.org/10.1074/jbc.M111.315648
http://www.eprints.iicb.res.in/1519/