Record Details

Induction of Apoptosis in Melanoma Cell by Attenuated Leishmanial Sphingolipid(s)

EPrints@IICB

View Archive Info
 
 
Field Value
 
Title Induction of Apoptosis in Melanoma Cell by Attenuated Leishmanial Sphingolipid(s)
 
Creator Ratha, Jagnyeswar
 
Subject Infectious Diseases and Immunology
 
Description Apoptosis is a process of deliberate life relinquishment by a cell in a multicellular organisms and involves an
orchestrated series of biochemical events leading to a characteristic cell morphology and death. It is executed in such a way as to safely dispose of cell corpses and fragments. In contrast to necrosis, which is a form of traumatic cell death that results from acute cellular injury, apoptosis is carried out in an orderly process that generally confers advantages during an organism's life cycle. In addition to its importance as a basic biological phenomenon, defective apoptotic processes have been implicated in an extensive variety of diseases. For instance, excessive apoptosis causes hypotrophy, such as in ischemic damage, whereas an insufficient amount results in uncontrolled cell proliferation, such as cancer.Cancer is a class of diseases characterized by uncontrolled division of cells and the ability of it to spread, either by direct growth into adjacent tissue through invasion, or by implantation in to distant sites by metastasis (where cancer cells are transported through by blood stream or lymphatic system). The most important reason behind the development and progression of cancer is the property of cancer cells to evade apoptosis. Selective induction of apoptosis in hyper proliferating cancer cells is thus considered as one of the attractive strategies to treat cancer.
 
Date 2007
 
Type Thesis
NonPeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1520/1/Jagnyeswar_Ratha_PDF.pdf
Ratha, Jagnyeswar (2007) Induction of Apoptosis in Melanoma Cell by Attenuated Leishmanial Sphingolipid(s). PhD thesis, Jadavpur University.
 
Relation http://www.eprints.iicb.res.in/1520/