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Synthesis, Characterization and Cytotoxicity study of Magnetic (Fe3O4)Nanoparticles and their Drug Conjugate

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Title Synthesis, Characterization and Cytotoxicity study of Magnetic (Fe3O4)Nanoparticles and their Drug Conjugate
 
Creator Banerji, Biswadip
Pramanik, Sumit Kumar
Mandal, Samir
Maiti, Nakul Chandra
Chaudhuri, Keya
 
Subject Molecular & Human Genetics
 
Description An easy synthesis of magnetic nanoparticles (Fe3O4) is described. Transmission electron microscopy
(TEM), atomic force microscopy (AFM), dynamic light scattering (DLS) and X-ray diffraction
(XRD) have been used to study the well dispersed and uniformly spherical nanoparticles.
5-Fluorouracil (5-FU) has been successfully loaded onto the nanoparticles and cytotoxicity studies
were performed using a standard MTT assay. The results indicate that 5-fluorouracil-loaded iron
nanoparticles are a more potent anticancer drug versus 5-fluorouracil alone
 
Date 2012
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1545/1/RSC_ADVANCES___2_(6)2493%2D2497_;2012[69].pdf
Banerji, Biswadip and Pramanik, Sumit Kumar and Mandal, Samir and Maiti, Nakul Chandra and Chaudhuri, Keya (2012) Synthesis, Characterization and Cytotoxicity study of Magnetic (Fe3O4)Nanoparticles and their Drug Conjugate. RSC Advances, 2 (6). pp. 2493-2497.
 
Relation http://dx.doi.org/10.1039/C2RA01118B
http://www.eprints.iicb.res.in/1545/