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Molecular and Functional Analysis of Genes Underlying Poag Pathogenesis

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Title Molecular and Functional Analysis of Genes Underlying Poag
Pathogenesis
 
Creator Banerjee, Deblina
 
Subject Molecular & Human Genetics
 
Description Glaucoma affects approximately 70 million people and is the second leading cause of irreversible blindness worldwide. Among the various subtypes, Primary open-angle glaucoma (POAG) is the most common form of this disease. POAG is a mutifactorial complex disorder where both environmental and genetic factors precipitate the disease. It has been suggested that 72% of POAG cases have some familial
component, but on rare occasion it follows a Mendelian pattern of inheritance. It is characterized by progressive loss of retinal ganglion cells and atrophy of the optic
nerve head, often associated with elevated intraocular pressure (IOP) caused by the reduced outflow of aqueous humor through the trabecular meshwork (TM), a meshwork of tissue chamber of the eye. disease pathogenesis.
The objectives of my study for this dissertation are:
a familial history of glaucoma or high intraocular pressure.
 
Date 2012
 
Type Thesis
NonPeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1659/2/Thesis_Deblina_Banerjee.pdf
Banerjee, Deblina (2012) Molecular and Functional Analysis of Genes Underlying Poag Pathogenesis. PhD thesis, Calcutta University.
 
Relation http://www.eprints.iicb.res.in/1659/