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Synthesis of Ether Backbone RNA NAnalogues and the Development of a Method for Carbohydrate Homologation

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Title Synthesis of Ether Backbone RNA NAnalogues and the Development of a Method for Carbohydrate Homologation
 
Creator Jana, Prithwish Kumar
 
Subject Chemistry
 
Description Carbohydrates having several chiral centers in their structures are potential starting materials for
the synthesis of many natural as well as biologically active non-natural products. Monosaccharide
is a single carbohydrate unit, and there are some higher-monosaccharide derivatives generally
called higher sugars that are not naturally occurring and some of them are very important from
biological point of view. This section of the work is primarily comprised of the synthesis of
higher sugars (formally C7- C10) starting from lower-membered monosaccharide, D-glucose along
with a short review on the reported synthesis of higher sugars. Basically, our synthetic strategy
involves with two effective reactions i.e., cross metathesis reaction and Sharpless asymmetric
dihydroxylation reaction. The small features of these two reactions have been described in the
thesis.
 
Date 2011
 
Type Thesis
NonPeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1661/1/Microsoft_Word_%2D_PKJ%2Dthesis%2DI.pdf
Jana, Prithwish Kumar (2011) Synthesis of Ether Backbone RNA NAnalogues and the Development of a Method for Carbohydrate Homologation. PhD thesis, Jadavpur University.
 
Relation http://www.eprints.iicb.res.in/1661/