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Synthesis of Some Novel Polynuclear Heteroaromatics Based on Quinolines and Isoquinolines

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Field Value
 
Title Synthesis of Some Novel Polynuclear
Heteroaromatics Based on Quinolines and Isoquinolines
 
Creator Mondal, Shyamal
 
Subject Chemistry
 
Description The thesis embodies the results of studies on “Synthesis of some novel polynuclear heteroaromatics mainly based on quinoline and isoquinoline”. Quinoline derivatives
are a class of synthetic antibiotics with broad spectrum antibacterial as well as antimalarial activities. The fused quinoline derivatives are also known to be effective in
the treatment of autoimmune conditions (such as rhenumatoid arthritis) with their anti inflammatory effects. Among the numerous structurally diverse derivatives many quinolines show significant biological activity such as quinine, morphine, and multifloramine. Hence, it is not surprising that this structural motif is also an important component in many of today’s pharmaceuticals. Nevertheless, the diversity
of quinoline as well as their biological and pharmaceutical relevance is still motivating academic and industrial researchers to look for new and improved syntheses for quinoline derivatives. Clearly, a number of practical methods have been developed for the synthesis of quinolines in the past century. More recently, especially transition metal catalysis has become a powerful tool for synthetic
methodology but chemical and biological research has now presented a great challenge to synthesize and optimise highly efficient and cost-effective synthetic
routes to some unique and novel biologically active substances.
 
Date 2012
 
Type Thesis
NonPeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1688/1/shyamal_mondal_Ph.D_Thesis.pdf
Mondal, Shyamal (2012) Synthesis of Some Novel Polynuclear Heteroaromatics Based on Quinolines and Isoquinolines. PhD thesis, Jadavpur University.
 
Relation http://www.eprints.iicb.res.in/1688/