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Identification and Characterization of the Enzymatic and Immunoregulatory Role of Plasmodial Macrophage Migration Inhibitory Factor in Host Pathology

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Title Identification and Characterization of the Enzymatic and Immunoregulatory Role of Plasmodial Macrophage Migration Inhibitory Factor in Host Pathology
 
Creator Alam, Athar
 
Subject Infectious Diseases and Immunology
 
Description Malaria remains one of the world’s most devastating infectious diseases. Approximately 3
billion people, one half of the world’s population, live in at-risk regions for malaria infection.
This leads to about 250 million malaria cases every year and nearly one million deaths (World
Malaria Report, WHO, 2011,
http://www.who.int/malaria/world_malaria_report_2011/en/index.html). The etiologic agent
Plasmodium falciparum (P. falciparum) is the major organism responsible for the majority of
deaths due to malaria, 90% of which occur in Africa with more than 85% in children under
the age of 5. The presence of widespread drug resistance is hampering the effectiveness of
most of the available drug arsenal (1, 2) with the notable exception of artemisinin-based
derivatives. In the battle to fight malaria, introduction of new drugs with novel mechanisms of
action is essential.
 
Date 2013-04-11
 
Type Thesis
NonPeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1865/1/Final_thesis.pdf
Alam, Athar (2013) Identification and Characterization of the Enzymatic and Immunoregulatory Role of Plasmodial Macrophage Migration Inhibitory Factor in Host Pathology. PhD thesis, Jadavpur University.
 
Relation http://www.eprints.iicb.res.in/1865/