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Interleukin 2 enhances natural killing of varicella-zoster virus-infected targets

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Title Interleukin 2 enhances natural killing of varicella-zoster virus-infected targets
 
Creator Ito , M
Bandyopadhyay , Santu
Matsumoto-Kobayashi, M
Clark, S C
Miller , Deborah
Starr, S E
 
Subject Infectious Diseases and Immunology
 
Description Preincubation of peripheral blood non-adherent mononuclear cells with purified or
recombinant interleukin 2 (IL-2) significantly enhanced natural killer (NK) activity
against uninfected and varicella-zoster virus (VZV)-infected targets, while antibodydependent
cellular cytotoxicity (ADCC) against VZV-infected targets was not increased.
Preincubation of effector cells with IL-2 had no effect on conjugate formation, but lysis of
both targets was increased in single cell assays. IL-2-enhanced NK against VZV-infected
targets was independent of gamma-interferon (y-IFN) production.
 
Date 1986
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1902/1/Clin_Exp_Immunol.__65%2C_182%2D189;1986.pdf
Ito , M and Bandyopadhyay , Santu and Matsumoto-Kobayashi, M and Clark, S C and Miller , Deborah and Starr, S E (1986) Interleukin 2 enhances natural killing of varicella-zoster virus-infected targets. Clinical experimental Immunology, 65. pp. 182-189.
 
Relation http://www.eprints.iicb.res.in/1902/