Record Details

Quercetin Improves Behavioral Deficiencies, Restores Astrocytes and Microglia, and Reduces Serotonin Metabolism in 3-Nitropropionic Acid-Induced Rat Model of Huntington’s Disease

EPrints@IICB

View Archive Info
 
 
Field Value
 
Title Quercetin Improves Behavioral Deficiencies, Restores Astrocytes and Microglia, and Reduces Serotonin Metabolism in

3-Nitropropionic Acid-Induced Rat Model of Huntington’s Disease
 
Creator Chakraborty, Joy
Singh, Raghavendra
Dutta, Debashis
Naskar, Amit
Rajamma, Usha
Mohanakumar, Kochupurackal P.
 
Subject Cell Biology & Physiology
 
Description Huntington’s disease (HD) is an autosomal dominant disorder, for which clinically available drugs offer only symptomatic relief. These prescription drugs are not free of side effects, and the patients usually suffer from anxiety and depression. We investigated quercetin,
a dietary flavonoid with free radical scavenging properties, for its beneficial potential if any, in 3-nitropropionic acid (3-NP)-induced HD in rats where both drugs were administered simultaneously.
 
Date 2014
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/2017/1/CNS_NEUROSCIENCE_%26_THERAPEUTICS__V_20(_1)10%2D19__;2014(34).pdf
Chakraborty, Joy and Singh, Raghavendra and Dutta, Debashis and Naskar, Amit and Rajamma, Usha and Mohanakumar, Kochupurackal P. (2014) Quercetin Improves Behavioral Deficiencies, Restores Astrocytes and Microglia, and Reduces Serotonin Metabolism in 3-Nitropropionic Acid-Induced Rat Model of Huntington’s Disease. CNS Neuroscience & Therapeutics, 20 (1). pp. 10-19.
 
Relation http://dx.doi.org/ 10.1111/cns.12189
http://www.eprints.iicb.res.in/2017/