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Transformation of cholic acid by Arthrobacter simplex

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Title Transformation of cholic acid by Arthrobacter simplex
 
Creator Mukherjee, Emele
Banerjee, Sukdeb
Mahato, Shashi B
 
Subject Chemistry
 
Description Fermentation of cholic acid with Arthrobacter simplex (ZZCB 227) under aerobic conditions yielded
3,12-dioxo-23,24-dinorchola_4,6dienoic acid, 7a-hydroxy-3,12-dioxo-23,24-dinorchoWenoic acid, 3a,
7a-dihydroxy-l2-oxo-5/3-cholan-24-oic acid, 3a,7~~-dihydroxy-12-0~0-5~-23,24-dinorcholan-22-oic acid,
7a,12a-dihydroxy-3-oxo-5P-cholan-24-oic acid, 7a-12a-dihydroxy-3-oxo-4-cholenoic acid, 7a,lZa-dihydroxy-
3-oxo-23,24-dinorchoM_enoic acid, and methyl-3a-7a,12a-trihydroxy-5fi-cholan-24-oate in addition
to a new metabolite 2P-hydroxy-3,12-dioxo-23,24-dinorchola-4,6-dienoic acid. Each microbial
metabolite was characterized by the application of various spectroscopic methods. The availability of
some of the metabolites’ enabled complete elucidation of their uC NMR spectra.
 
Publisher Elsevier
 
Date 1993
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/2322/1/STEROIDS__V._58_(_10_)_484%2D490;1993[21].pdf
Mukherjee, Emele and Banerjee, Sukdeb and Mahato, Shashi B (1993) Transformation of cholic acid by Arthrobacter simplex. Steroids, 58 (10). pp. 484-490.
 
Relation http://www.eprints.iicb.res.in/2322/