Record Details

Synthetic, structural, electrochemical and DNA-binding aspects of a novel oximato bridged copper(II) dimer

EPrints@IICB

View Archive Info
 
 
Field Value
 
Title Synthetic, structural, electrochemical and DNA-binding aspects of a novel oximato bridged copper(II) dimer
 
Creator Guhathakurta, Bhargab
Basu, Pritha
Kumar, Gopinatha Suresh
Lu, Liping
Zhu, Miaoli
Bandyopadhyay, Nirmalya
Naskar, Jnan Prakash
 
Subject Chemistry
 
Description A dimeric double oximato-bridged (l1,2-N-O) Cu(II) complex, [Cu2L2(ClO4)2]�2H2O (1), was synthesized from the reaction of equimolar proportion of a novel Schiff base ligand, 1-phenyl-1-(pyridin-2-yl-hydrazono)- propan-2-one oxime (LH), and copper(II)perchlorate hexahydrate in methanol. C, H and N microanalyses, gravimetric copper estimation, FT-IR, UV–Vis (solid state as well as in solution), ESI-MS spectra,
molar electric conductivity, EPR and room temperature magnetic susceptibility measurements were performed
to characterize 1. The X-ray crystal structure of 1 shows that each copper center in 1 is in ‘N3O2’ coordination environment with a Cu� � �Cu separation of 3.595 Å. 1 follows unique two-step mono-electronic oxidative steps in its CV in methanol. ESI-MS spectrum of 1 indicates that the dimeric core unit retains its identity in solution as well. Interaction of 1 with Calf thymus (CT) DNA was studied by spectroscopic and calorimetric techniques. The mode of binding was investigated by ethidium bromide displacement
assay. This binding enhanced the stabilization of the DNA structure against thermal strand separation. The magnitudes of the association constant as derived from spectroscopic and calorimetric studies are in good harmony
 
Publisher Elsevier
 
Date 2016
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/2692/1/Polyhedron_110_(2016)_227%E2%80%93234.pdf
Guhathakurta, Bhargab and Basu, Pritha and Kumar, Gopinatha Suresh and Lu, Liping and Zhu, Miaoli and Bandyopadhyay, Nirmalya and Naskar, Jnan Prakash (2016) Synthetic, structural, electrochemical and DNA-binding aspects of a novel oximato bridged copper(II) dimer. Polyhedron, 110. pp. 227-234.
 
Relation http://www.eprints.iicb.res.in/2692/