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Response of pro-inflammatory prostaglandin contents in anti-inflammatory supplements from green mussel Perna viridis L. in a time-dependent accelerated shelf-life study

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Relation http://eprints.cmfri.org.in/12622/
https://www.sciencedirect.com/science/article/pii/S1756464614000048
 
Title Response of pro-inflammatory prostaglandin
contents in anti-inflammatory supplements from
green mussel Perna viridis L. in a time-dependent
accelerated shelf-life study
 
Creator Chakraborty, Kajal
Chakkalakal, Selsa Jose
Joseph, Deepu
 
Subject Bioactive compound
 
Description The effect of natural antioxidant additives on pro-inflammatory prostaglandins, PGE2 and
PGF2a vis-a` -vis C20n-6 fatty acid in the green mussel, Perna viridis extract (MSL) and those of
MSL supplemented with additives (in GMET1 through GMET4) were investigated in an accelerated
shelf-life study (50 �C) of 90 days. HPLC was employed for quantifying PGE2 and PGF2a
and their chemical structures were assigned by signature peaks based on ESI-LC–MS and 1H
NMR. The concentrations of PGE2 and PGF2a after an accelerated shelf-life study of 90 days
were significantly higher (P < 0.05) in MSL on day 90 of the intervention than among GMET2
and GMET4. An inverse correlation between antioxidative effects of the additives and proinflammatory
eicosanoids in GMET2 and GMET4 at baseline and at the end of the study was
apparent. The results describe the utility of quantifying PGE2 and PGF2a as an index of antioxidant
status and lipid peroxidation
 
Date 2014
 
Type Article
PeerReviewed
 
Format text
 
Language en
 
Identifier http://eprints.cmfri.org.in/12622/1/Journal%20of%20Functional%20Foods_2014_Kajal%20Chakraborty_Response%20of%20proinflammatory%20prostaglandin%20contents.pdf
Chakraborty, Kajal and Chakkalakal, Selsa Jose and Joseph, Deepu (2014) Response of pro-inflammatory prostaglandin contents in anti-inflammatory supplements from green mussel Perna viridis L. in a time-dependent accelerated shelf-life study. Journal of Functional Foods, 7. pp. 527-540.