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Analysis Of Intermolecular Interactions In Pharmaceutical Salts And Cocrystals

Electronic Theses of Indian Institute of Science

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Field Value
 
Title Analysis Of Intermolecular Interactions In Pharmaceutical Salts And Cocrystals
 
Creator Dasgupta, Archi
 
Subject Intermolecular Interactions
Pharmaceutical Salts
Cocrystals
Lamotrigine Complexes
Entacapone - Amine Complexes
Multicomponent Crystals
Active Pharmaceutical Ingredients (APIs)
Pharmaceutical Solids
Theoretical Chemistry
 
Description The studies on cocrystals and salts presented in the the chapters clearly bring out the influence of intermolecular interactions as the main evaluators of the cocrystal-salt regime. The observations made in Chapter 2 indicate that in case if the cocrystal formation is through hydrogen bonds the location of the proton decides the nature of the complex in the energy landscape. The observation that the coformer controls the topology of intermolecular space as demonstrated in Chapter 3 provides insights into the importance of directionality rather than strength of intermolecular interactions. Indeed halogen bonding in cocrystals gain importance in this context.
 
Contributor Row, T N Guru
 
Date 2013-07-17T10:04:26Z
2013-07-17T10:04:26Z
2013-07-17
2011-06
 
Type Thesis
 
Identifier http://etd.iisc.ernet.in/handle/2005/2123
http://etd.ncsi.iisc.ernet.in/abstracts/2727/G24775-Abs.pdf
 
Language en_US
 
Relation G24775