Record Details

Marine Microbes as a source of Antimicrobial Compounds

CMFRI Repository

View Archive Info
 
 
Field Value
 
Relation http://eprints.cmfri.org.in/13024/
 
Title Marine Microbes as a source of Antimicrobial Compounds
 
Creator Chakraborty, Kajal
Vinaya, K K
Antony, Tima
Joy, Minju
Sreemol, C K
 
Subject Bioactive compounds
 
Description Microbial natural products that have reached the market without any chemical
modifications are a testimony to the remarkable ability of microorganisms to produce druglike
small molecules. Although still in clinical trails, a feature example of this is salinosporamide
A (NPI-0052), a novel anticancer agent found in the exploration of new marine environments
(Fenical et al., 2009). In 2008, over 1000 marine natural products were reported (Blunt et al.,
2010). However, out of 19 microbial-derived drugs reported in 2008, no natural products
from marine microbes were present, signifying the novelty of their systematic exploration
(Ganesan, 2008). Currently, >30 compounds of marine microbial origin are in clinical or
preclinical studies for the treatment of different types of cancer (Simmons et al., 2005)
clearly demonstrating that marine microorganisms have become an essential resource in
the discovery of new antibiotic leads.
 
Date 2018
 
Type Conference or Workshop Item
NonPeerReviewed
 
Format text
 
Language en
 
Identifier http://eprints.cmfri.org.in/13024/1/Winter%20School_Recent%20Advances_Bioactive%20compounds_Chapter%2014.pdf
Chakraborty, Kajal and Vinaya, K K and Antony, Tima and Joy, Minju and Sreemol, C K (2018) Marine Microbes as a source of Antimicrobial Compounds. In: Winter School on “Recent advances in bioactive compounds from marine organisms and development of high value products for health management, ICAR-Central Marine Fisheries Research Institute, Kochi.