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<p>Anti-hyperlipidaemic effects of fresh and cured <em>Bhallataka Kshaudra </em>(<em>Semecarpus anacardium</em> L.) in animals</p>

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Title Statement <p>Anti-hyperlipidaemic effects of fresh and cured <em>Bhallataka Kshaudra </em>(<em>Semecarpus anacardium</em> L.) in animals</p>
 
Added Entry - Uncontrolled Name Nariya, Mukesh B; Institute of Post Graduate Teaching & Research in Ayurveda (Funded by M/o AYUSH, Govt of India, New Delhi)
Dwivedi, Mohan Krishna; Gujarat Ayurved University, Jamnagar
Galib, R ; Gujarat Ayurved University, Jamnagar
Prajapati, Pradeep Kumar; Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar
Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar
 
Uncontrolled Index Term Anti-hyperlipidaemia; Bhallataka; curing; Polyphenolic compounds; Semecarpus anacardium L
 
Summary, etc. <p style="text-align: justify;"><em>Bhallataka Phala</em> (fruit of <em>Semecarpus anacardium</em> L.), is a well-known anti-hyperlipidaemic drug. <em>Bhallataka</em> is described in all Ayurvedic<em> </em>classics as <em>Rasayana </em>and<em> </em>advocated<em> </em>for<em> </em>various therapeutic purposes such<em> </em>as <em>Kushtha </em>(skin diseases), <em>Arsha</em> (piles),<em> Krimi </em>(worm infestations), <em>Prameha </em>(urine disorders)<em>, Medodosha </em>(lipid disorders)<em>, </em>etc. Though its anti-hyperlipidaemic activity has been studied; actual differentiation in their therapeutic efficacy due to storage period has yet not been attempted on experimental animals. This prompted to initiate a comparative anti-hyperlipidemic activity of fixed oil (expressed oil) i.e. non-volatile in nature collected from fresh <em>Bhallataka</em> and four months old (cured) <em>Bhallataka</em> samples against cholesterol diet induced hyperlipidaemia in rats.<strong> </strong>Hyperlipidemia was induced by oral administration of cholesterol (20 % suspension in coconut oil, 5 mL/kg) in morning hours and hydrogenated vegetable oil (5 mL/kg) in evening. The effect of drugs was assessed on body weight, serum biochemical and histological parameters. Both drugs produced significant attenuation of the relative weight of liver in cholesterol-fed animals. Cured sample of <em>Bhallataka </em>provided better effect in lowering serum cholesterol (21.98 %), triglyceride (60.23 %), VLDL (56.82 %); while fresh sample of <em>Bhallataka</em> also<em> </em>found to be effective in lowering serum cholesterol (20.69 %), serum triglyceride (45.59 %), VLDL (46.59 %) in comparison to control group<em>. </em>From the result of the present study, it is concluded that the cured sample of <em>Bhallataka</em> has pronounced anti-hyperlipidemic effect than the fresh sample in experimentally-induced hyperlipidemia in rats.</p>
 
Publication, Distribution, Etc. Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]
2018-09-25 12:39:37
 
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http://op.niscair.res.in/index.php/IJNPR/article/view/16016
 
Data Source Entry Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 9, ##issue.no## 2 (2018): June, 2018
 
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