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FREE SKIN GRAFTS IN THE TREATMENT OF LARGE WOUNDS WITH AND WITHOUT THE USE OF PLATELET RICH PLASMA – A COMPARATIVE CLINICAL STUDY IN DOGS

KrishiKosh

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Title FREE SKIN GRAFTS IN THE TREATMENT OF LARGE WOUNDS WITH AND WITHOUT THE USE OF PLATELET RICH PLASMA – A COMPARATIVE CLINICAL STUDY IN DOGS
 
Creator KONKA, PREETHI
 
Contributor Dr.V., Gireesh Kumar
 
Subject grafting, biological phenomena, hides and skins, organic compounds, biological development, granules, fruits, application methods, area, harvesting
 
Description The present clinical study on reconstruction of skin defects using partial thickness mesh skin grafts was performed on ten dogs with twelve wounds, in Department of Veterinary Surgery and Radiology, College of Veterinary Science, Rajendranagar, Hyderabad and Teaching Veterinary Clinical Complex at Veterinary Hospital, Bhoiguda, Secunderabad. Following clinical examination, the twelve wounds from ten dogs, that were unamenable to primary closure, were selected for the present study irrespective of breed, sex and age.
In twelve wounds out of the ten dogs, the wounds were reported to be caused by trauma in nine dogs and ulcerated wound due to self mutilation in one dog. No other concurrent illness was found in any of the dogs. All twelve wounds were reconstructed with partial thickness mesh skin grafting technique in which six wounds were assigned to
group–I and remaining six wounds were similarly reconstructed followed by injection of PRP were assigned to group-II.
For nine dogs with traumatic skin wounds, the recipient bed was prepared two days prior to skin grafting technique, by scraping off the unhealthy chronic granulation bed with a BP blade No. 11. In one dog with chronic ulcerated wound on elbow region took four days for formation of healthy granulation bed. The result was found satisfactory as the fresh granulation bed appeared bright, beef red in color on the day of surgery. A general soft tissue surgery set, Watson’s skin graft knife and sterile skin graft blades were used for performing the technique.
Platelet Rich Plasma was prepared prior to grafting by double centrifugation technique at 800 rpm and 1600 rpm for 10 minutes respectively. The prepared Platelet Rich Plasma was injected in between the graft and recipient bed in the wounds of group-II dogs. Ten wounds out of twelve, from both the groups healed by 15th post-operative day with variable graft viability in each wound. Remaining two wounds showed sloughing of graft which was allowed to heal by second intension healing. The wounds of group-II dogs, showed early graft “take” by 7th to 10th post-operative day with reduced edema and exudates when compared to group-I wounds. Hair growth from graft site was noticed from 15th
The lateral thoracic region was preferred for harvesting the graft in all the wounds. The donor site evinced pain while changing the dressings for first seven post-operative days. Then subsequently the dogs did not show any discomfort and the donor site healed by 15 post-operative day in both the groups.
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First bandage change was performed 72 hours following skin graft surgery, and the subsequent bandage change was done every alternate day. post-operative day with minimal scar formation without any complications.
It was concluded from the present study that, partial thickness mesh skin grafting procedure yield good results for correction of skin defects. The wounds reconstructed with partial thickness mesh skin graft with injection of PRP showed early primary healing and reduced healing time with no difference in graft viability between the two groups tested. Further, more studies with greater sample size need to be undertaken in this area to establish PRP as a validated treatment modality.
 
Date 2016-12-27T12:40:38Z
2016-12-27T12:40:38Z
2016-10-04
 
Type Thesis
 
Identifier http://krishikosh.egranth.ac.in/handle/1/93193
 
Relation D;488
 
Format application/pdf
 
Publisher PVNR TVU