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Modelling and analysis of blood flow in an artery having mild stenosis with and without bypass: effects of blood and wall characteristics

Shodhganga@INFLIBNET

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Title Modelling and analysis of blood flow in an artery having mild stenosis with and without bypass: effects of blood and wall characteristics
 
Contributor Singh, S P
Shukla, J B
 
Subject Mathematics
Stenosis
 
Description Severe stenosis may cause critical flow conditions related to artery collapse, plaque cap rupture
which leads directly to stroke and heart attack. Stroke and ischemic heart disease, which result
from high grade stenosis, are the single most common causes of death in the United States. High
grade stenosis increases flow resistance in arteries which forces the body to raise the blood
pressure to maintain the necessary blood supply. Both the high pressure and the narrowing of
blood vessel cause high flow velocity, high shear stress and low shear stress. These may be
related to thrombus formation, atherosclerosis growth and plaque cap rupture which leads directly
to stroke and heart attack. The exact mechanism of this complicated process is still not well
understood. A better study in this physiological process is of great importance to early diagnosis,
prevention and treatment stenosis related diseases. Current investigations are now focusing on complex branching structures and on the smaller
scaled problems of artery and capillary flow. In particular, mathematical models are developed to
describe blood flow in the heart and the cardiovascular system, as well as the transport of oxygen and carbon dioxide through the respiratory system. These models are largely used to simulate
blood flow in arteries and to predict dynamical patterns in physiological and pathological
conditions. Our specific interest is in modeling the flow of blood, which is a mixture of interacting gel-filled blood cells and fluid plasma. The oxygenated blood is transported from lungs to different parts of body. The transportation is carried out by hemoglobin present inside the erythrocytes or red cells.
Many nutrient materials such as glucose, vitamin etc. dissolved in plasma are carried by the blood
to the plasma cells for maintaining the constant functioning of blood cells.
References p. 140-146
 
Date 2014-01-02T07:08:08Z
2014-01-02T07:08:08Z
2014-01-02
23-03-2009
29-06-2012
30-11-2013
 
Type Ph.D.
 
Identifier http://hdl.handle.net/10603/14562
 
Language English
 
Relation 52
 
Rights university
 
Format 146p.
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None
 
Coverage Mathematics
 
Publisher Agra
Dayalbag Educational Institute
Department of Mathematics
 
Source University