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Total phenolic and flavonoid content, antioxidant effects and antidiarrheal activity of balacaturbhadrika churna – an Ayurvedic preparation

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Title Statement Total phenolic and flavonoid content, antioxidant effects and antidiarrheal activity of balacaturbhadrika churna – an Ayurvedic preparation
 
Added Entry - Uncontrolled Name Ram, HN Aswatha
Pratap, Rahul
Chandrashekar, K S
Pai, Vasudev
Khan, Saleemulla
Kamath, Venkatesh
 
Uncontrolled Index Term ABTS; Antidiarrheal; Antioxidant; Balacaturbhadrika churna; DPPH; Flavonoid; Phenolic
 
Summary, etc. <p class="Abstract">Balacaturbhadrika churna (BC) is an important pediatric preparation in Ayurveda. It is used to treat various diseases of gastro-intestinal tract particularly diarrhea in children. Free radicals cause oxidative damage in the intestine and are correlated with its diseases. In the current study, total phenolic and flavonoid contents of BC extracts were determined and their antioxidant evaluation in various <em>in vitro</em> models was carried out. Procedures mentioned in The Ayurvedic Formulary of India were followed to prepare in-house BC; alcoholic (BCAL) and aqueous (BCAQ) extracts were prepared and tested by standard procedures. BCAL was tested for antidiarrheal activity in castor oil induced model. The ethanolic extract showed better antioxidant activity in many of the models as compared to aqueous extract. The present study showed substantial amounts of flavonoids and phenolics in churna extracts. BCAL showed significant antidiarrheal activity against the tested model. The potential antioxidant and antidiarrheal activities displayed by Balacaturbhadrika churna extracts could be attributed to these contents.</p>
 
Publication, Distribution, Etc. Indian Journal of Traditional Knowledge (IJTK)
2019-07-18 15:58:02
 
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http://op.niscair.res.in/index.php/IJTK/article/view/26731
 
Data Source Entry Indian Journal of Traditional Knowledge (IJTK); ##issue.vol## 18, ##issue.no## 3 (2019): Indian Journal of Traditional Knowledge
 
Language Note en