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Methylenetetrahydrofolate reductase gene (C677T and A1298C) polymorphisms and hyperhomocysteinemia as risk factors for Myocardial Infarction

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Title Statement Methylenetetrahydrofolate reductase gene (C677T and A1298C) polymorphisms and hyperhomocysteinemia as risk factors for Myocardial Infarction
 
Added Entry - Uncontrolled Name Eissa, Adil A
Rasool, Chiman Saleem
Mustafa, Majeed Hussein
 
Uncontrolled Index Term Hyperhomocysteinemia; Kurds; Methylenetetrahydrofolate reductase; Myocardial infarction
 
Summary, etc. <p style="text-align: justify;">Conflicting data concerning the association between methylenetetrahydrofolate reductase gene <em>MTHFR</em> (C677T and A1298C) polymorphisms with or without hyperhomocysteinemia and myocardial infarction exists and data from developing countries is limited thus, a current study initiated to study whether any association exist between the above polymorphisms and myocardial infarction among Kurdish patients from Duhok province/Iraq.</p> <p style="text-align: justify;">A case-control study was performed in Azadi teaching hospital/Duhok/Iraq and included 75 patients with acute myocardial infarction and 75 age and sex-matched normal controls. All the patients and controls had their methylenetetrahydrofolate reductase gene analyzed for C677T and A1298C polymorphism using polymerase chain reaction/restriction fragment length polymorphism technique as well as their homocysteine level.</p>
 
Publication, Distribution, Etc. Indian Journal of Biochemistry and Biophysics (IJBB)
2019-08-19 11:28:31
 
Electronic Location and Access application/pdf
http://op.niscair.res.in/index.php/IJBB/article/view/27363
 
Data Source Entry Indian Journal of Biochemistry and Biophysics (IJBB); ##issue.vol## 56, ##issue.no## 4 (2019): IJBB Vol.56(4) [August 2019]
 
Language Note en