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Free radicals and antioxidants in normal versus cancerous cells — An overview

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Title Statement Free radicals and antioxidants in normal versus cancerous cells — An overview
 
Added Entry - Uncontrolled Name Shrivastava, Anju
Aggarwal, Lalit Mohan
Mishra, Surendra Pratap
Khanna, Hari Dev
Shahi, Uday Pratap
Pradhan, Satyajit
 
Uncontrolled Index Term Cancer therapy; Reactive oxygen species (ROS); Superoxides; Xenobiotic
 
Summary, etc. Oxygen is vital for aerobic processes of metabolism and respiration- It has been also implicated in many diseases and degenerative conditions. Free radicals formed from reactive oxygen and nitrogen species act as key players in the initiation and progression of tumor cells and enhance their metastatic potential. The imbalance in the formation and use of free radicals in the tissue creates oxidative stress. Inadequacy in normal cells antioxidant defense system or excessive free radical formation or even both can cause the cell to experience the oxidative stress. This review outlines the involvement of free radicals in different aspects of cancer, from prevention to initiation, progression, treatment and to reduce morbidity and mortality.
 
Publication, Distribution, Etc. Indian Journal of Biochemistry and Biophysics (IJBB)
2019-08-26 16:17:48
 
Electronic Location and Access application/pdf
http://op.niscair.res.in/index.php/IJBB/article/view/27728
 
Data Source Entry Indian Journal of Biochemistry and Biophysics (IJBB); ##issue.vol## 56, ##issue.no## 1 (2019): IJBB Vol.56(1) [February 2019]
 
Language Note en