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Prediction of vitamin interacting residues in a vitamin binding protein using evolutionary information.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Prediction of vitamin interacting residues in a vitamin binding protein using evolutionary information.
 
Creator Panwar, Bharat
Gupta, Sudheer
Raghava, G.P.S.
 
Subject QR Microbiology
 
Description The vitamins are important cofactors in various enzymatic-reactions. In past, many inhibitors have been designed against vitamin binding pockets in order to inhibit vitamin-protein interactions. Thus, it is important to identify vitamin interacting residues in a protein. It is possible to detect vitamin-binding pockets on a protein, if its tertiary structure is known. Unfortunately tertiary structures of limited proteins are available. Therefore, it is important to develop in-silico models for predicting vitamin interacting residues in protein from its primary structure.
 
Publisher BMC part of Springer Nature
 
Date 2013-02-07
 
Type Article
PeerReviewed
 
Relation https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-14-44
http://crdd.osdd.net/open/2449/
 
Identifier Panwar, Bharat and Gupta, Sudheer and Raghava, G.P.S. (2013) Prediction of vitamin interacting residues in a vitamin binding protein using evolutionary information. BMC bioinformatics, 14. p. 44. ISSN 1471-2105