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Effect of cinnamon supplementation on resistin and ghrelin in obese diabetic men

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Title Statement Effect of cinnamon supplementation on resistin and ghrelin in obese diabetic men
 
Added Entry - Uncontrolled Name Sfar, Myriam
Hfaiedh, Kmar Ben
Mahrez, Kamel Ben
Skhiri, Hajer Aounallah
Rayana, Chihab Ben
Chemli, Rachid
Mami, Faika Ben
Slama, Fethi Ben
 
Uncontrolled Index Term Cinnamon; Diabetes; Ghrelin; Obesity; Resistin
 
Summary, etc. <p>The object of this study was to determine the effect of Cinnamomum zeylanicum (cinnamon) on glycemic/lipid balance, resistin and ghrelin. 84 obese Type 2 diabetic patients were assigned in 2 groups which consumed 8 g and 4 g of cinnamon powder. Anthropometric, hormonal and biochemical parameters were measured before and after 10 weeks of treatment. We found that cinnamon decrease BMI and waist circumference respectively of -5.52±1.47 kg/m² and -10.72±6.12 cm for group 2 of and a decrease of -4.45±1.46 kg/m² and -6.86±5.5 cm in group 1. Our results also showed a decrease of the glucose level of -1,173±0, 75 mmol/L in group 2 and -0, 8932±0, 72 mmol/L in group 1 and a decrease of insulin levels <br /> of -3.24±2.85 μUI/L in group 2 and -2.54±2.8 μUI/L in group 1. The assays showed that resistin secretion decreased <br /> by -2.08±1.09 ng/mL for the 8 g dose and -1.59±0.926 ng/mL for the 4 g dose, and there was an increase in ghrelin secretion of +1.55±2.21 μg/mL for the 8 g dose and + 2.49±1.13 μg/mL for the 4 g dose.</p> The results confirmed the anti-hyperglycemic and hypolipidemic effects of cinnamon opening a new approach to studying how the compounds derived from certain spices regulate the endogenous release of hormones such as ghrelin and resistin for therapeutic intervention.
 
Publication, Distribution, Etc. Indian Journal of Traditional Knowledge (IJTK)
2019-10-18 12:46:46
 
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http://op.niscair.res.in/index.php/IJTK/article/view/29003
 
Data Source Entry Indian Journal of Traditional Knowledge (IJTK); ##issue.vol## 18, ##issue.no## 4 (2019): Indian Journal of Traditional Knowledge
 
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