Record Details

Hypoallergen Peanut Lines Identified Through Large-Scale Phenotyping of Global Diversity Panel: Providing Hope Toward Addressing One of the Major Global Food Safety Concerns

OAR@ICRISAT

View Archive Info
 
 
Field Value
 
Relation http://oar.icrisat.org/11345/
https://doi.org/10.3389/fgene.2019.01177
doi:10.3389/fgene.2019.01177
 
Title Hypoallergen Peanut Lines Identified Through Large-Scale Phenotyping of Global Diversity Panel: Providing Hope Toward Addressing One of the Major Global Food Safety Concerns
 
Creator Pandey, A K
Sudini, H
Upadhyaya, H D
Varshney, R K
Pandey, M K
 
Subject Groundnut
Genetics and Genomics
Food and Nutrition
Germplasm
 
Description Peanut allergy is one of the serious health concern and affects more than 1% of the
world’s population mainly in Americas, Australia, and Europe. Peanut allergy is sometimes
life-threatening and adversely affect the life quality of allergic individuals and their families.
Consumption of hypoallergen peanuts is the best solution, however, not much effort has
been made in this direction for identifying or developing hypoallergen peanut varieties.
A highly diverse peanut germplasm panel was phenotyped using a recently developed
monoclonal antibody-based ELISA protocol to quantify five major allergens. Results
revealed a wide phenotypic variation for all the five allergens studied i.e., Ara h 1 (4–36,833
μg/g), Ara h 2 (41–77,041 μg/g), Ara h 3 (22–106,765 μg/g), Ara h 6 (829–103,892 μg/g),
and Ara h 8 (0.01–70.12 μg/g). The hypoallergen peanut genotypes with low levels of
allergen proteins for Ara h 1 (4 μg/g), Ara h 2 (41 μg/g), Ara h 3 (22 μg/g), Ara h 6 (829 μg/g), and Ara h 8 (0.01 μg/g) have paved the way for their use in breeding and
genomics studies. In addition, these hypoallergen peanut genotypes are available for use in cultivation and industry, thus opened up new vistas for fighting against peanut allergy problem across the world.
 
Publisher Frontiers Media
 
Date 2019-11
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Identifier http://oar.icrisat.org/11345/1/fgene-10-01177.pdf
Pandey, A K and Sudini, H and Upadhyaya, H D and Varshney, R K and Pandey, M K (2019) Hypoallergen Peanut Lines Identified Through Large-Scale Phenotyping of Global Diversity Panel: Providing Hope Toward Addressing One of the Major Global Food Safety Concerns. Frontiers in Genetics (TSI), 10 (1177). pp. 1-15. ISSN 1664-8021