<strong>Synthesis and characterization of magnetic imprinted polymer for selective extraction of cephalexin from food matrices</strong>
Online Publishing @ NISCAIR
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Authentication Code |
dc |
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Title Statement |
<strong>Synthesis and characterization of magnetic imprinted polymer for selective extraction of cephalexin from food matrices</strong> |
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Added Entry - Uncontrolled Name |
Aggarwal, Sneha ; National Dairy Research Institute Rajput, Yudhishthir Singh; National Dairy Research Institute Nanda, Dhiraj Kumar; National Dairy Research Institute Sharma, Rajan ; National Dairy Research Institute Singh, Gulab ; National Dairy Research Institute National Agricultural Science Fund (NASF) (Grant No.30019), Government of India |
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Uncontrolled Index Term |
Antibiotic extraction; Cephalexin; Imprinted polymer; Magnetic imprinted polymer; Selectivity |
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Summary, etc. |
Magnetic imprinted polymer having selectivity for cephalexin has been synthesized and evaluated for extraction of the antibiotic from selected food matrix. Fe<sub>3</sub>O<sub>4</sub> magnetite has been prepared by co-precipitation of FeCl<sub>2</sub>.4H<sub>2</sub>O and FeCl<sub>3</sub>.6H<sub>2</sub>O in 1:2 molar ratios. Imprinted polymer has been synthesized by polymerization of methacrylic acid and ethylene glycol dimethacrylate in the presence of cephalexin over the surface of Fe<sub>3</sub>O<sub>4</sub> magnetite. Selectivity of imprinted polymer over non-imprinted polymer is determined under different solvent conditions. Selectivity in both methanol and acetonitrile is found to be > 35. Selectivity is <em>p</em>H dependent in aqueous buffer solution and is in range of 2.33 to 21.3, maximum being at <em>p</em>H 5.0. Electrostatic interaction between amino group of cephalexin and carboxylic group in polymer appears to be main force contributing to selectivity of imprinted polymer. Cephalexin imprinted magnetic polymer extracted 80, 88, 63 and 78% cephalexin from water, milk, honey and egg white, respectively. |
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Publication, Distribution, Etc. |
Indian Journal of Chemical Technology (IJCT) 2019-12-16 12:40:27 |
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Electronic Location and Access |
application/pdf http://op.niscair.res.in/index.php/IJCT/article/view/18570 |
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Data Source Entry |
Indian Journal of Chemical Technology (IJCT); ##issue.vol## 26, ##issue.no## 5 (2019): Indian Journal of Chemical Technology |
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Language Note |
en |
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