Characterization of DEAD-box family of RNA helicases in tomato provides insights into their roles in biotic and abiotic stresses
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Title |
Characterization of DEAD-box family of RNA helicases in tomato provides insights into their roles in biotic and abiotic stresses
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Creator |
Pandey, Saurabh
Muthamilarasan, Mehanathan Sharma, Namisha Chaudhry, Vaishali Dulani, Priya Shweta, Shweta Jha, Sarita Mathur, Saloni Prasad, Manoj |
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Subject |
RNA helicase
DEAD-box RNA helicase Disease resistance Tomato leaf curl New Delhi virus Abiotic stress Tomato (Solanum lycopersicum) |
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Description |
Accepted date: 27 November 2018
In plants, RNA helicases play significant roles in growth, development and stress response. In a previous study, a three-fold upregulation of a DEAD-box RNA helicase in a tomato cultivar tolerant to Tomato leaf curl New Delhi virus (ToLCNDV) as compared to susceptible cultivar during virus infection was shown. Given this, a comprehensive study was performed to identify the members of RNA helicase family in tomato and analyze their functional properties in response to abiotic stresses, hormone treatments and ToLCNDV infection. A total of 131 genes were identified and classified into DEAD- (42), DEAH- (38), and DExD/H-box (51) RNA helicases. Expression profiling of candidate genes in response to abiotic stresses and ToLCNDV infection in contrasting tomato cultivars suggested the putative roles of SlDEAD23 and SlDEAD35 in biotic and abiotic stresses. Heterologous overexpression of these genes in yeast enhanced the tolerance of transgenic cells to salt and cold stresses. Further, virus-induced silencing of SlDEAD35 in ToLCNDV tolerant cultivar resulted in susceptibility to virus infection, thus suggesting its involvement in tolerance mechanism. Altogether, this study provides novel insights into the structure, organization and involvement of DEAD-box RNA helicase genes in biotic and abiotic stress responses in tomato. This work was supported by the Core Grant of National Institute of Plant Genome Research, New Delhi, India. Saurabh Pandey acknowledges the Department of Biotechnology, Govt. of India for the research fellowship. Mehanathan Muthamilarasan acknowledge the DST INSPIRE Faculty Award from Department of Science and Technology, Govt. of India. Authors also acknowledge Prof. Savithramma DineshKumar, Plant Biology Department, University of California, Davis, USA for providing TRV-VIGS vectors. The authors are also thankful to DBTeLibrary Consortium (DeLCON) for providing access to the e-resources. |
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Date |
2019-01-02T05:57:12Z
2019-01-02T05:57:12Z 2019 |
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Type |
Article
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Identifier |
Environmental and Experimental Botany, 158: 107-116
0098-8472 http://223.31.159.10:8080/jspui/handle/123456789/906 https://www.sciencedirect.com/science/article/pii/S009884721830950X https://doi.org/10.1016/j.envexpbot.2018.11.018 |
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Language |
en_US
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Format |
application/pdf
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Publisher |
Elsevier B.V.
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