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Epigenetics and epigenomics of plants

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Title Epigenetics and epigenomics of plants
 
Creator Yadav, Chandra Bhan
Pandey, Garima
Muthamilarasan, Mehanathan
 
Subject Epigenetics
Epigenomics of Plants
 
Description Accepted date: 23 Jan 2018
The genetic material DNA in association with histone proteins forms the complex structure called chromatin, which is prone to undergo modification through certain epigenetic mechanisms including cytosine DNA methylation, histone modifications, and small RNA-mediated methylation. Alterations in chromatin structure lead to inaccessibility of genomic DNA to various regulatory proteins such as transcription factors, which eventually modulates gene expression. Advancements in high-throughput sequencing technologies have provided the opportunity to study the epigenetic mechanisms at genome-wide levels. Epigenomic studies using high-throughput technologies will widen the understanding of mechanisms as well as functions of regulatory pathways in plant genomes, which will further help in manipulating these pathways using genetic and biochemical approaches. This technology could be a potential research tool for displaying the systematic associations of genetic and epigenetic variations, especially in terms of cytosine methylation onto the genomic region in a specific cell or tissue. A comprehensive study of plant populations to correlate genotype to epigenotype and to phenotype, and also the study of methyl quantitative trait loci (QTL) or epiGWAS, is possible by using high-throughput sequencing methods, which will further accelerate molecular breeding programs for crop improvement.
C.B.Y. acknowledges the Science and Engineering Research Board, Department of Science and Technology, Govt. of India, India for providing a Young Scientist Research Grant (File No. YSS/2015/000287). Ms. Garima Pandey and Mr. Mehanathan Muthamilarasan thank the University Grants Commission for Research Fellowship.
 
Date 2018-01-29T07:26:30Z
2018-01-29T07:26:30Z
2018
 
Type Book chapter
 
Identifier In: Varshney RK, Pandey MK, Chitikineni A (eds), Advances in Biochemical Engineering/Biotechnology: Plant Genetics and Molecular Biology, Springer International Publishing, Switzerland, pp 237-261.
0724-6145
http://223.31.159.10:8080/jspui/handle/123456789/831
https://link.springer.com/chapter/10.1007%2F10_2017_51
https://doi.org/10.1007/10_2017_51
 
Language en_US
 
Format application/pdf
 
Publisher Springer