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Recent advances in small RNA mediated plant-virus interactions

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Title Recent advances in small RNA mediated plant-virus interactions
 
Creator Prasad, Ashish
Sharma, Namisha
Muthamilarasan, Mehanathan
Rana, Sumi
Prasad, Manoj
 
Subject Small RNA (sRNA)
microRNA (miRNA)
small interfering RNA (siRNA)
plant immunity
plant-virus interactions
antiviral defense
DNA methylation
 
Description Accepted date: 10 February 2019
Small RNAs (sRNA) are reported to play pivotal roles in the epigenetic and post-transcriptional regulation of gene expression during growth, development, and stress response in plants. Recently, the involvement of two different classes of sRNAs namely, miRNAs (microRNAs), and siRNAs (small interfering RNAs) in biotic stress response has been underlined. Notably, during virus infection, these sRNAs deploy antiviral defense by regulating the gene expression of the modulators of host defense pathways. As a counter defense, viruses have evolved strategic pathways involving the production of suppressors that interfere with the host silencing machinery. This molecular arms race between the sophisticated gene regulatory mechanism of host plants fine-tuned by sRNAs and the defense response exhibited by the virus has gained much attention among the researchers. So far, several reports have been published showing the mechanistic insights on sRNA-regulated defense mechanism in response to virus infection in several crop plants. In this context, our review enumerates the molecular mechanisms underlying host immunity against viruses mediated by sRNAs, the counter defense strategies employed by viruses to surpass this immunogenic response and the advances made in our understanding of plant-virus interactions. Altogether, the report would be insightful for the researchers working to decode the sRNA-mediated defense response in crop plants challenged with virus infection.
This research was financially supported by the core grant of National Institute of Plant Genome Research (NIPGR), New Delhi, India and TATA Innovation Fellowship awarded to Dr. Manoj Prasad by the Department of Biotechnology (DBT), Ministry of Science & Technology, Govt. of India, India (File no. BT/HRD/35/01/02/2017). Ashish Prasad acknowledges the Council of Scientific and Industrial Research, Govt. of India, India for the award of research fellowship. Dr. Mehanathan Muthamilarasan acknowledges the INSPIRE Faculty Award from the Department of Science and Technology, Govt. of India, India. The authors are thankful to DBT-eLibrary Consortium
(DeLCON) for providing access to e-resources.
 
Date 2019-04-11T10:50:52Z
2019-04-11T10:50:52Z
2019
 
Type Article
 
Identifier Critical Reviews in Biotechnology, 39(4): 587-601
1549-7801
http://223.31.159.10:8080/jspui/handle/123456789/941
https://www.tandfonline.com/doi/abs/10.1080/07388551.2019.1597830?journalCode=ibty20
https://doi.org/10.1080/07388551.2019.1597830
 
Language en_US
 
Format application/pdf
 
Publisher Taylor & Francis Group