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<p>Efficient synthesis of new oxadiazole-thiazole hybrids using (diacetoxyiodo)benzene</p>

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Title Statement <p>Efficient synthesis of new oxadiazole-thiazole hybrids using (diacetoxyiodo)benzene</p>
 
Added Entry - Uncontrolled Name Sumran, Garima ; Department of Chemistry D. A. V. College (Lahore), Ambala City 134 003, Haryana, India
Rani, Chinu ; Department of Chemistry, Kurukshetra University, Kurukshetra
Aggarwal, Ranjana ; Department of Chemistry, Kurukshetra University, Kurukshetra
Council of Scientific and Industrial Research, New Delhi, India
 
Uncontrolled Index Term 2-Aryl-5-(2'-(4-nitrophenylamino)thiazol-4'-yl)-1,3,4-oxadiazoles, 2-(4-nitrophenylamino)-N'-arylidenethiazole-4-carbohydrazide, (diacetoxyiodo)benzene, oxidative cyclization, oxadiazole-thiazole hybrid
 
Summary, etc. <p style="text-align: justify;">An efficient synthesis of some new 2-aryl-5-(2'-(4-nitrophenylamino)thiazol-4'-yl)-1,3,4-oxadiazoles 7a-e, has been accomplished through oxidative cyclization of 2-(4-nitrophenylamino)-N'-(substituted benzylidene) thiazole-4-carbohydrazides 6a-e using an ecofriendly oxidant, (diacetoxyiodo)benzene at ambient temperature. The structures of the synthesized oxadiazole-thiazole hybrid compounds have been characterized by elemental and spectral (IR, 1H and 13C NMR, and MS) analysis. The reaction can tolerate a wide range of aldehydes to afford the corresponding unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles. The mild reaction conditions, relatively benign nonmetallic oxidant and short reaction time are noteworthy advantages of this methodology.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section B (IJC-B)
2020-02-11 16:28:55
 
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http://op.niscair.res.in/index.php/IJCB/article/view/27852
 
Data Source Entry Indian Journal of Chemistry -Section B (IJC-B); ##issue.vol## 59, ##issue.no## 1 (2020): Indian Journal of Chemistry -Section B
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJCB/article/download/27852/465486984
http://op.niscair.res.in/index.php/IJCB/article/download/27852/465486985
http://op.niscair.res.in/index.php/IJCB/article/download/27852/465486986
 
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