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Title Organophosphorus insecticide, methyl parathion toxicity in labeo rohita
 
Names Sivaperumal, P.
Sankar, T.V.
Date Issued 2013 (iso8601)
Abstract The effects of three sublethal concentrations of
Methyl Parathion (MP) toxicity were evaluated in
freshwater fish Labeo rohita. Lipid peroxidation
(LPO) and antioxidant enzymes viz., superoxide
dismutase (SOD, EC 1.15.1.1), catalase (CAT, EC
1.11.1.6), glutathione peroxidase (GPx, EC 1.11.1.9),
glutathione S-transferase (GST, EC 2.5.1.18) and total
reduced glutathione (GSH EC 1.6.4.2) were estimated
in liver and the neurotoxic effects were
investigated by the determination of acetylcholinesterase
(AChE, EC 3.1.1.7) activities in brain of Labeo
rohita of size 75 ± 6 g at sub lethal exposure. The
exposure to MP at 1.0 mg L-1 increased LPO by twofold
and in 45 days almost five-fold increase was
observed when compared to control. SOD activity
increased by three-fold (0.5 mg L-1) and six-fold (1
mg L-1) at sub lethal exposure of MP. The AChE
activity decreased with increase in the concentration
of MP. The results show that changes in antioxidant
enzymes system and inhibition of AChE activity can
be used as biomarkers of exposure to MP in aquatic
ecosystems
Genre Article
Topic Methyl parathion
Identifier Fishery Technology 2013: 50 (3), 231-236