Record Details

DSpace at CIFT

View Archive Info
 

Metadata

 
Field Value
 
Title Resistance of Escherichia coli and Salmonella isolated from marine and freshwater fishes towards Carbapenems
 
Names Rao, M.B.
Murthy, L.N.
Jesmi, D.
Prasad, M.M.
Date Issued 2014 (iso8601)
Abstract The carbapenems are beta-lactam antimicrobial agents
with an exceptionally broad spectrum of activity and
are active against most Enterobacteriaceae including
those that produce ampC b-lactamase. Resistance to
carbapenems, especially carbapenems-resistant-Enterobacteriaceae
(CRE) is a serious issue worldwide as
it is extremely difficult to combat bacteria resistant
to carbapenems. Fifty two isolates of Escherichia coli
and twelve isolates of Salmonella (invA and stn gene
positive) isolated from marine fish and freshwater
fish were tested for their susceptibility to carbapenems
namely meropenem, imipenem and ertapenem. A
low percentage (3.9%) of E.coli showed resistance to
meropenem, while 11.5 & 17% of E.coli and 8.3 &
25% of Salmonella showed intermediate sensitivity
to meropenem and ertapenem, respectively. However,
100% of E. coli and Salmonella were sensitive
to imipenem. Importantly, meropenem resistant
E.coli was also found to be resistant to other
antibiotics such as ciprofloxacin, gentamicin, nalidixic
acid, norfloxacin and tetracycline. The results
indicate that carbapenem resistance in E. coli and
Salmonella isolated from fish was marginal but
nevertheless needs continuous monitoring.
Genre Article
Topic Carbapenems
Identifier Fishery Technology 2014: 51(3), 207-212