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Field | Value |
Title | Protective Effects of Echinorhinus brucus Liver Oil against Induced Inflammation and Ulceration in Rats |
Names |
Vishnu, K.V.
Ajeeshkumar, K.K. Asha, K.K. Remyakumari, K.R. Ganesan, B. Anandan, R. Chatterjee, N.S. Suseela Mathew |
Date Issued | 2015 (iso8601) |
Abstract | Anti-inflammatory and anti-ulcer activities of Bramble shark (Echinorhinus brucus) liver oil were examined in rats. The oil showed significant proportion of n-3 polyunsaturated fatty acids (PUFAs), the percentages of EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) being 16 and 18% respectively. The study also revealed that liver oil had a very favourable n3:n6 ratio of 4.7. Oral administration of shark liver oil at 1g kg-1 concentration significantly attenuated the formalin-induced paw edema in experimental rats. It exerted potent anti-ulcer effect against acid-ethanol mixturemediated lesion formation in the rat gastric mucosa. |
Genre | Article |
Topic | Bramble shark |
Identifier | Fishery Technology 2015: 52 (4), 252-257 |