Root-specific expression of chickpea cytokinin oxidase/dehydrogenase 6 leads to enhanced root growth, drought tolerance and yield without compromising nodulation
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Title |
Root-specific expression of chickpea cytokinin oxidase/dehydrogenase 6 leads to enhanced root growth, drought tolerance and yield without compromising nodulation
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Creator |
Khandal, Hitaishi
Gupta, Santosh Kumar Dwivedi, Vikas Mandal, Drishti Sharma, Nilesh Kumar Vishwakarma, Niraj Kumar Pal, Lalita Choudhary, Megha Francis, Aleena Malakar, Paheli Singh, Nagendra Pratap Sharma, Kapil Sinharoy, Senjuti Singh, Narendra Pratap Sharma, Rameshwar Chattopadhyay, Debasis |
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Subject |
CaCKX6
Cicer arietinum L cytokinin drought-tolerance mineral root |
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Description |
Accepted date: 17 March 2020
Cytokinin group of phytohormones regulate root elongation and branching during post‐embryonic development. Cytokinin degrading enzymes cytokinin oxidases/dehydrogenases (CKXs) have been deployed to investigate biological activities of cytokinin and to engineer root growth. We expressed chickpea cytokinin oxidase 6 (CaCKX6) under the control of a chickpea root‐specific promoter of CaWRKY31 in Arabidopsis thaliana and chickpea having determinate and indeterminate growth patterns, respectively, to study the effect of cytokinin depletion on root growth and drought tolerance. Root‐specific expression of CaCKX6 led to a significant increase in lateral root number and root biomass in Arabidopsis and chickpea without any penalty to vegetative and reproductive growth of shoot. Transgenic chickpea lines showed increased CKX activity in root. Soil‐grown advanced chickpea transgenic lines exhibited higher root‐to‐shoot biomass ratio and enhanced long‐term drought tolerance. These chickpea lines were not compromised in root nodulation and nitrogen fixation. The seed yield in some lines was up to 25% higher with no penalty in protein content. Transgenic chickpea seeds possessed higher levels of zinc, iron, potassium and copper. Our results demonstrated the potential of cytokinin level manipulation in increasing lateral root number and root biomass for agronomic trait improvement in an edible legume crop with indeterminate growth habit. The project is funded by the Department of Biotechnology (DBT), Ministry of Science and Technology, Government of India (BT/PR3304/AGR/02/815/2011 and BT/HRD/35/01/03/2014 to DC) and (Grant no. BT/PR11671/PBD/16/828/2008 to RS) and National Institute of Plant Genome Research, India. LP, MC & PM is supported by SRF & JRF fellowship from Council of Scientific and Industrial Research (CSIR, Govt. of India). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The assistance of central instrumentation facilities of NIPGR in various experiments is acknowledged. The authors are grateful to the DBT-eLibrary Consortium (DeLCON) for providing access to eResources. The authors have no conflicts of interest to declare. |
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Date |
2020-03-30T15:40:25Z
2020-03-30T15:40:25Z 2020 |
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Type |
Article
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Identifier |
Plant Biotechnology Journal, 18(11): 2225-2240
1467-7652 https://doi.org/10.1111/pbi.13378 https://onlinelibrary.wiley.com/doi/10.1111/pbi.13378 http://223.31.159.10:8080/jspui/handle/123456789/1049 |
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Language |
en_US
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Format |
application/pdf
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Publisher |
John Wiley & Sons
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