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Study on single nucleotide polymorphisms of H -FABP gene in sheep

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Title Study on single nucleotide polymorphisms of H -FABP gene in sheep
 
Creator Qiao, H.Y.
Zhao, Q.J.
Yao, N.
Lu, Y.-Z.
Meng, X.-R.
Guan, Wei-Jun
Ma, Y.H.
Han Jianlin
 
Subject genetics
sheep
 
Description PCR-SSCP and DNA sequencing approaches were applied to assess the single nucleotide polymorphisms (SNPs) and analyze the genetic polymorphisms at partial exon 2 and intron 2 of H-FABP(Heart fatty acid-binding protein)gene, and five sheep populations that comprised of Small-Tailed Han sheep (SH, 48), Ningxia Tan sheep (Tan, 121), Tan × SH F1 (23), Poll Dorset (48) and Suffolk (24) sheep were screened in this stuty. The result showed: (1)four SNPs at 981(G/A), 1014(A/C) 1019(T/C) and 1058 (-/G) and nine genotypes (AA, BB, CC, AB, AC, BC, AD, CD and BD) were detected using primer 2, the AA was the predominant genotype. A chi-square analysis suggested that the allele frequencies and genotype frequencies of H-FABP were in Hardy-Weinberg equilibrium except the Tan and Suffolk populations. Statistical analysis revealed a low polymorphism information content (PIC) in the Suffolk and Tan × SH F1 populations (PIC< 0.25) but an intermediate PIC in the remaining three populations (0.25< PIC
 
Date 2009-08-14
2010-08-04T13:29:08Z
2010-08-04T13:29:08Z
 
Type Journal Article
 
Identifier Qiao, H.-Y., Zhao, Q.-J., Yao, N., Lu, Y.-Z., Meng, X.-R., Jianlin, H., Guan, W.-J.; Ma, Y.-H. 2009. Study on single nucleotide polymorphisms of H -FABP gene in sheep. Hereditas (Beijing) 31(7):725-731.
0253-9772
https://hdl.handle.net/10568/2168
https://doi.org/10.3724/SP.J.1005.2009.00725
 
Language zh
 
Rights Limited Access
 
Format p. 725-731
 
Publisher China Science Publishing & Media Ltd.
 
Source Hereditas