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Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus

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Title Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus
 
Creator Downing, T.
Lynn, D.J.
Connel, S.
Lloyd, A.T.
Bhuiyan, A.K.F.H.
Silva, P.
Naqvi, A.N.
Sanfo, R.
Sow, R.S.
Overseas Development Institute
Hanotte, Olivier H.
O'Farrelly, C.O.
Bradley, D.
 
Subject CHICKENS
ANIMAL DISEASES
 
Description Olivier Hanotte is ILRI author
The comparative analysis of genome sequences emerging for several avian species with the fully sequenced chicken genome enables the genome-wide investigation of selective processes in functionally important chicken genes. In particular, because of pathogenic challenges it is expected that genes involved in the chicken immune system are subject to particularly strong adaptive pressure. Signatures of selection detected by inter-species comparison may then be investigated at the population level in global chicken populations to highlight potentially relevant functional polymorphisms.
 
Date 2010-04-11T20:02:01Z
2010-04-11T20:02:01Z
2009-06-15
 
Type Journal Article
 
Identifier Downing, T.; Lynn, D.J.; Connell, S.; Lloyd, A.T.; Bhuiyan, A.K.F.H.; Silva, P.; Naqvi, A.N.; Sanfo, R.; Sow, R-S.; Podisi, B.; Hanotte, O.; O'Farelly, C.O.; Bradley, D. 2009. Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus. BMC Evolutionary Biology. 9:136-149.
1471-2148
http://hdl.handle.net/10568/1176
 
Language en
 
Source BMC Evolutionary Biology