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The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia

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Title The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia
 
Creator Vordermeier, M.
Ameni, G.
Berg, S.
Bishop, Richard P.
Robertson, B.D.
Aseffa, A.
Hewinson, R.G.
Young, D.B.
 
Subject tuberculosis
animal diseases
cattle
 
Description Bovine tuberculosis in domestic livestock such as cattle is an economically important disease with zoonotic potential, particularly in countries with emerging economies. We discuss the findings of recent epidemiological and immunological studies conducted in Ethiopia on host susceptibility differences between native zebu and the exotic Holstein–Friesian cattle that are increasingly part of the Ethiopian National herd, due to the drive to increase milk yields. These findings support the hypothesis that native Zebu cattle are more resistant to bovine tuberculosis. We also summarise the results of experimental infections that support the epidemiological data, and of laboratory experiments that suggest a role for the innate immune response, and in particular interleukin-6, in the outcome of bovine tuberculosis infection.
 
Date 2012-05-01
2012-02-06T19:53:35Z
2012-02-06T19:53:35Z
 
Type Journal Article
 
Identifier Vordermeier, M., Ameni, G., Berg, S., Bishop, R., Robertson, B.D., Aseffa, A., Hewinson, R.G. and Young, D.B. 2012. The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia. Comparative Immunology, Microbiology and Infectious Diseases 35(3): 227-232.
https://hdl.handle.net/10568/16437
https://doi.org/10.1016/j.cimid.2012.01.003
 
Language en
 
Rights CC-BY-4.0
Open Access
 
Format p. 227-232
 
Source Comparative Immunology, Microbiology and Infectious Diseases