Field studies of drug-resistant cattle trypanosomes in Kenedougou Province, Burkina Faso
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Title |
Field studies of drug-resistant cattle trypanosomes in Kenedougou Province, Burkina Faso
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Creator |
McDermott, John J.
Woitag, T. Sidibe, I. Bauer, B. Diarra, B. Ouedraogo, D. Kamuanga, M. Peregrine, A.S. Eisler, M.C. Zessin, K.H. |
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Subject |
BURKINA FASO
CATTLE PHYTOMONAS DRUG RESISTANCE ANTIPROTOZOAL AGENTS TRYPANOSOMIASIS INFECTION |
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Description |
Field studies were conducted to assess the occurrence of resistance to isometamidium chloride and diminazene aceturate in trypanosomes infecting cattle in Kenedougou Province of Burkina Faso. Forty-five of the 166 villages in Kenedougou were randomly sampled and visited to assess livestock numbers, trypanosomosis risk, and tsetse challenge. The proportion of cattle infections associated with drug-resistant trypanosomes was assessed in the nine villages with the highest trypanosome infection prevalence and one village with a confirmed history of drug-resistant infections. These studies showed that resistance to both isometamidium and diminazene was widespread. However, there was considerable variation between villages in drug-resistance parameters, with the proportion of treated cattle with trypanosome infections 3 months after isometamidium prophylaxis varying from 6.9 to 63.8% and the proportion of cattle having infections 2 weeks after treatment with diminazene varying from 0 to 36.8%. The demonstration of widespread resistance to both isometamidium and diminazene has important implications, as administration of trypanocides is the most commonly employed method to control trypanosomosis in this area.
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Date |
2013-06-11T09:25:38Z
2013-06-11T09:25:38Z 2003 |
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Type |
Journal Article
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Identifier |
Acta Tropica;86(1): 93-103
0001-706X http://hdl.handle.net/10568/29969 |
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Language |
en
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Source |
Acta Tropica
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