Record Details

Field studies of drug-resistant cattle trypanosomes in Kenedougou Province, Burkina Faso

CGSpace

View Archive Info
 
 
Field Value
 
Title Field studies of drug-resistant cattle trypanosomes in Kenedougou Province, Burkina Faso
 
Creator McDermott, John J.
Woitag, T.
Sidibe, I.
Bauer, B.
Diarra, B.
Ouedraogo, D.
Kamuanga, M.
Peregrine, A.S.
Eisler, M.C.
Zessin, K.H.
 
Subject BURKINA FASO
CATTLE
PHYTOMONAS
DRUG RESISTANCE
ANTIPROTOZOAL AGENTS
TRYPANOSOMIASIS
INFECTION
 
Description Field studies were conducted to assess the occurrence of resistance to isometamidium chloride and diminazene aceturate in trypanosomes infecting cattle in Kenedougou Province of Burkina Faso. Forty-five of the 166 villages in Kenedougou were randomly sampled and visited to assess livestock numbers, trypanosomosis risk, and tsetse challenge. The proportion of cattle infections associated with drug-resistant trypanosomes was assessed in the nine villages with the highest trypanosome infection prevalence and one village with a confirmed history of drug-resistant infections. These studies showed that resistance to both isometamidium and diminazene was widespread. However, there was considerable variation between villages in drug-resistance parameters, with the proportion of treated cattle with trypanosome infections 3 months after isometamidium prophylaxis varying from 6.9 to 63.8% and the proportion of cattle having infections 2 weeks after treatment with diminazene varying from 0 to 36.8%. The demonstration of widespread resistance to both isometamidium and diminazene has important implications, as administration of trypanocides is the most commonly employed method to control trypanosomosis in this area.
 
Date 2013-06-11T09:25:38Z
2013-06-11T09:25:38Z
2003
 
Type Journal Article
 
Identifier Acta Tropica;86(1): 93-103
0001-706X
http://hdl.handle.net/10568/29969
 
Language en
 
Source Acta Tropica