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Evaluation of oraquick® HIV-1/2 as oral rapid test

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Title Evaluation of oraquick® HIV-1/2 as oral rapid test
 
Creator Nkenfou, C.N.
Kembou, J.E.
Temgoua, E.S.
Djikeng, Appolinaire
Mouafo, L.M.
Ndzie, E.N.
Donkam, I.
Colizzi, V.
SanouSobze, M.
 
Subject human diseases
health
 
Description As Cameroon scales up its national HIV/AIDS control program, evaluating the performance of commercially available tests for accurate and cost effective diagnostics becomes essential. A cross-sectional study assessed the performance
of an HIV oral rapid test. A total of 1520 participants consented to participate in the study. After counselling, they were tested for HIV using the national algorithm followed by OraQuick. Results of the national algorithm were compared to those
of OraQuick, for sensitivity, specificity, positive predictive and negative predictive values. 62% of participants were male, and 1% was reported HIV-positive following the national algorithm. The OraQuick test had 93% sensitivity, 99% specificity, 99.93% NPV and 90% PPV (95% CI, Kappa 0.965). Though more expensive (2-6x) compared to the national algorithm tests, oral mucosal transudate-based test demonstrated good performance. Therefore, it could be implemented in resource constrained settings if subsidized and could increase participation since less invasive with no blood accident exposure.
 
Date 2013
2015-09-30T10:55:51Z
2015-09-30T10:55:51Z
 
Type Journal Article
 
Identifier Nkenfou, C.N., Kembou, J.E., Temgoua, E.S., Djikeng, A., Mouafo, L.M., Ndzie, E.N., Donkam, I., Colizzi, V. and SanouSobzé, M. 2013. Evaluation of Oraquick® HIV-1/2 as oral rapid test. African Journal of Infectious Diseases 7: 27-30.
2006-0165
https://hdl.handle.net/10568/68343
https://doi.org/10.4314/ajid.v7i2.2
 
Language en
 
Rights Open Access
 
Format p. 27-30
 
Publisher African Journals Online
 
Source African Journal of Infectious Diseases