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Changes in serum proteins and immune response in oreochromis mossambicus induced by aflatoxin B

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Relation http://eprints.cmfri.org.in/120/
 
Title Changes in serum proteins and immune response
in oreochromis mossambicus induced by aflatoxin B
 
Creator Zacharia, Sherly
Thomas, P C
Paulton, M P
 
Subject Fish and Fisheries
 
Description Studies were conducted to evaluate the molecular changes induced by aflatoxin,
the most frequently encountered dietary carcinogen in Oreochromis
mossambicus. Three sub-lethal test doses of aflatoxin B1 incorporated in feed
(1.5, 5.0 and 15.0mg/kg feed) were given to the fishes for a period of 30 days and
the changes in serum protein profile were resolved through SDS PAGE at regular
intervals. Similarly, the changes in immune responses were also studied. The
study revealed significant changes in both protein profile and immune response
in the experimental fishes compared to the control, indicating that the toxin
exerts its effect even at sublethal levels.
 
Publisher CMFRI/ICAR
 
Date 2003
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Identifier http://eprints.cmfri.org.in/120/1/IJF-4_Oct-Dec_-_1.pdf
Zacharia, Sherly and Thomas, P C and Paulton, M P (2003) Changes in serum proteins and immune response in oreochromis mossambicus induced by aflatoxin B. Indian Journal of Fisheries, 50 (4). pp. 421-426.