ICAR Research Data Repository for Knowledge Management
Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays
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View Archive Info| Field | Value | |
| Title |
Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays
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| Creator |
Rennie, C.
Noyes, H.A. Kemp, Stephen J. Hulme, H. Brass, A. Hoyle, D.C. |
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| Subject |
GENETICS
LIVESTOCK |
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| Description |
Microarrays are an important and widely used tool. Applications include capturing genomic DNA for high-throughput sequencing in addition to the traditional monitoring of gene expression and identifying DNA copy number variations. Sequence mismatches between probe and target strands are known to affect the stability of the probe-target duplex, and hence the strength of the observed signals from microarrays.
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| Date |
2010-08-07T12:07:26Z
2010-08-07T12:07:26Z 2008-07-03 |
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| Type |
Journal Article
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| Identifier |
Rennie, C.; Noyes, H.A.; Kemp, S.J.; Hulme, H.; Brass, A.; Hoyle, D.C. 2008. Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays. BMC Genomics 9:317.
1471-2164 https://hdl.handle.net/10568/2202 |
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| Language |
en
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| Source |
BMC Genomics
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