First report of antioxidant abeo-labdane type diterpenoid from intertidal red seaweed Gracilaria salicornia with 5-lipoxygenase inhibitory potential
CMFRI Repository
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Relation |
http://eprints.cmfri.org.in/14266/
https://www.tandfonline.com/doi/abs/10.1080/14786419.2018.1508150?journalCode=gnpl20 https://doi.org/10.1080/14786419.2018.1508150 |
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Title |
First report of antioxidant abeo-labdane type diterpenoid from intertidal red seaweed Gracilaria salicornia with 5-lipoxygenase inhibitory potential
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Creator |
Antony, Tima
Chakraborty, Kajal |
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Subject |
New record
Bioactive compounds Biochemistry Seaweed Fish Biotechnology |
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Description |
Phytochemical investigation on the biologically active compounds of seaweed Gracilaria salicornia {(C. Agardh) E.Y. Dawson} (family Gracilariaceae) guided to the separation of a previously unreported abeo-labdane class of diterpenoid. The compound was characterized as methyl-16(13→14)-abeo-7-labdene-(12-oxo) carboxylate by extensive spectroscopic experiments, and comparison with the related compounds. The studied compound registered significantly greater activities against pro-inflammatory 5-lipoxygenase (IC50 0.86 mg/mL) than that exhibited by non-steroidal anti-inflammatory agent ibuprofen (IC50 0.92 mg/mL, P
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Publisher |
Taylor and Francis
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Date |
2020
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Type |
Article
PeerReviewed |
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Format |
text
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Language |
en
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Identifier |
http://eprints.cmfri.org.in/14266/1/Natural%20Product%20Research_2020_Kajal%20Chakraborty_First%20report%20of%20antioxidant%20abeo%20labdane%20type%20diterpenoid%20from%20intertidal%20red%20seaweed%20Gracilaria%20salicornia%20with%205%20lipoxygenase%20inhibitory%20potential.pdf
Antony, Tima and Chakraborty, Kajal (2020) First report of antioxidant abeo-labdane type diterpenoid from intertidal red seaweed Gracilaria salicornia with 5-lipoxygenase inhibitory potential. Natural Product Research, 34 (10). pp. 1409-1416. ISSN 1478-6427 (Online) |
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