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First report of antioxidant abeo-labdane type diterpenoid from intertidal red seaweed Gracilaria salicornia with 5-lipoxygenase inhibitory potential

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Relation http://eprints.cmfri.org.in/14266/
https://www.tandfonline.com/doi/abs/10.1080/14786419.2018.1508150?journalCode=gnpl20
https://doi.org/10.1080/14786419.2018.1508150
 
Title First report of antioxidant abeo-labdane type diterpenoid from intertidal red seaweed Gracilaria salicornia with 5-lipoxygenase inhibitory potential
 
Creator Antony, Tima
Chakraborty, Kajal
 
Subject New record
Bioactive compounds
Biochemistry
Seaweed
Fish Biotechnology
 
Description Phytochemical investigation on the biologically active compounds of seaweed Gracilaria salicornia {(C. Agardh) E.Y. Dawson} (family Gracilariaceae) guided to the separation of a previously unreported abeo-labdane class of diterpenoid. The compound was characterized as methyl-16(13→14)-abeo-7-labdene-(12-oxo) carboxylate by extensive spectroscopic experiments, and comparison with the related compounds. The studied compound registered significantly greater activities against pro-inflammatory 5-lipoxygenase (IC50 0.86 mg/mL) than that exhibited by non-steroidal anti-inflammatory agent ibuprofen (IC50 0.92 mg/mL, P 
 
Publisher Taylor and Francis
 
Date 2020
 
Type Article
PeerReviewed
 
Format text
 
Language en
 
Identifier http://eprints.cmfri.org.in/14266/1/Natural%20Product%20Research_2020_Kajal%20Chakraborty_First%20report%20of%20antioxidant%20abeo%20labdane%20type%20diterpenoid%20from%20intertidal%20red%20seaweed%20Gracilaria%20salicornia%20with%205%20lipoxygenase%20inhibitory%20potential.pdf
Antony, Tima and Chakraborty, Kajal (2020) First report of antioxidant abeo-labdane type diterpenoid from intertidal red seaweed Gracilaria salicornia with 5-lipoxygenase inhibitory potential. Natural Product Research, 34 (10). pp. 1409-1416. ISSN 1478-6427 (Online)