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<p>Lead Nitrate Induced Histopathological Alterations in the Liver and Intestine of African Catfish <em>Clarias gariepinus </em>Exposed to Sublethal Concentrations</p><span style="white-space: pre;"> </span>

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Title Statement <p>Lead Nitrate Induced Histopathological Alterations in the Liver and Intestine of African Catfish <em>Clarias gariepinus </em>Exposed to Sublethal Concentrations</p><span style="white-space: pre;"> </span>
 
Added Entry - Uncontrolled Name Warith, Abdel-Wahab A Abdel; Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia, P.O. Box 2455, Riyadh – 11451
Younis, Elsayed M; Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia, P.O. Box 2455, Riyadh – 11451
Al-Asgah, Nasser ; Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia, P.O. Box 2455, Riyadh – 11451
Ebaid, Hossam ; Department of Zoology, College of Science, El-Minia University, Egypt
Elsayed, Elsayed A; Department of Natural and Microbial Products, National Research Centre, Dokki, Cairo, Egypt
 
Uncontrolled Index Term Histological examinations; Liver; Intestine; Lead nitrate
 
Summary, etc. <p>Studies were carried out on the liver and intestine tissue of <em>Clarias gariepinus </em>after exposure to sublethal concentrations of LC<sub>50 </sub>lead nitrate for 20 days. Fish were distributed into four groups, control (0 mg/L, LC<sub>50</sub> of Pb(NO<sub>3</sub>)<sub>2</sub>) and three groups exposed to 20, 40 and 60% of the LC<sub>50</sub> of Pb(NO<sub>3</sub>)<sub>2</sub> (16.12, 32.24 and 48.37 mg/L respectively). Section of hepatic and intestine tissues showed the normal structure for control group. However, treated hepatic tissues of fish exhibited altered its characteristic architecture, with remarkably high vacuolation in hepatocytes and hepatoctolysis. Also, central vein was dilated and increased hemorrhage in the sections of almost samples from treated fish. Increased number of fibroblasts and Kuppffer cells were observed in the examined sections from treated fish when compared to the control. Therefore, fish treated with 60% LD<sub>50</sub> of Pb(NO<sub>3</sub>)<sub>2</sub> observed the proliferation of fibrous in connective tissue particularly near sinusoids and substituting liver parenchyma. Therefore, intestinal sections from the different treated fish groups revealed an evident harmful to intestinal tissue, especially in enterocytes and structures of villi. Also, disturbed longitudinal and circular muscularis were observed, to abnormally dilated, lamina propria, was infiltrated with a huge numbers of inflammatory leukocytes. Mucous secreting goblet cells proliferated and multiplied in all exposed fish.</p>
 
Publication, Distribution, Etc. Journal of Scientific and Industrial Research (JSIR)
2020-08-26 14:54:13
 
Electronic Location and Access application/pdf
http://op.niscair.res.in/index.php/JSIR/article/view/39646
 
Data Source Entry Journal of Scientific and Industrial Research (JSIR); ##issue.vol## 79, ##issue.no## 06
 
Language Note en