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Theoretical insight into the antioxidant, electronic and anticancer behaviour of simmondsin

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Field Value
 
Title Theoretical insight into the antioxidant, electronic and anticancer behaviour of simmondsin
 
Creator Kiraz, Aslı Öztürk
 
Subject Anticancer therapeutic agent
Cytochrome P450
Molecular docking
Simmondsin
 
Description 530-538
Simmondsin is a type of flavonoid it belongs to the group of flavan-3-ols (or simply flavanols (phenols). Phenolic compounds are known as antioxidants. In this study, we explain simmondsin’s antioxidant mechanism and investigate it to determine if it can be used as an anticancer therapeutic agent or not. Our results show that simmondsin is a very strong antioxidant that prefers hydrogen atom transfer (HAT) mechanism and can be benefited as an anticancer therapeutic agent. Hence, it can be used in cancer drugs to decrease the harmful effects of cancer cure.
 
Date 2020-09-30T05:51:55Z
2020-09-30T05:51:55Z
2020-10
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://nopr.niscair.res.in/handle/123456789/55373
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJBB Vol.57(5) [October 2020]