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Plant-based stearidonic acid as sustainable source of omega-3 fatty acid with functional outcomes on human health.

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Relation http://ir.cftri.com/14471/
https://doi.org/10.1080/10408398.2020.1765137
 
Title Plant-based stearidonic acid as sustainable source of omega-3 fatty acid with
functional outcomes on human health.
 
Creator Prasad, P.
Anjali, P.
Sreedhar, R. V.
 
Subject 04 Functional foods
20 Plant Food
 
Description Dietary omega-3 long chain polyunsaturated fatty acids (n-3 LC-PUFA) like eicosapentaenoic acid
(EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3) are known to be potent biological regulators with therapeutic and preventive effects on human health. Many global health organizations
have recommended consuming marine based omega-3 sources for neonatal brain development
and reducing the risk of various chronic diseases. However, due to concerns regarding the origin,
sustainable supply and safety of the marine sources, alternative n-3 PUFA sources are being
explored. Recently, plant-based omega-3 sources are gaining much importance because of their
sustainable supply and dietary acceptance. a-linolenic acid (ALA, 18:3n-3) rich seed oils are the
major omega-3 fatty acid source available for human consumption. But, efficiency of conversion of
ALA to n-3 LC-PUFAs in humans is limited due to a rate-limiting step in the n-3 pathway catalyzed
by D6-desaturase. Botanical stearidonic acid (SDA, 18:4n-3) rich oils are emerging as a sustainable
omega-3 source with efficient conversion rate to n-3 LC-PUFA especially to EPA, as it bypasses the
D6-desaturase rate limiting step. Several recent studies have identified the major plant sources of
SDA and explored its potential health benefits and preventive roles in inflammation, cardiovascular
disease (CVD) and cancer. This systematic review summarizes the current state of knowledge on
the sources, nutraceutical roles, food-based applications and the future perspectives of botanical SDA.
 
Date 2020
 
Type Article
PeerReviewed
 
Format pdf
 
Language en
 
Identifier http://ir.cftri.com/14471/1/CRITICAL%20REVIEWS%20IN%20FOOD%20SCIENCE%20AND%20NUTRITION%202020.pdf
Prasad, P. and Anjali, P. and Sreedhar, R. V. (2020) Plant-based stearidonic acid as sustainable source of omega-3 fatty acid with functional outcomes on human health. Critical Reviews in Food Science and Nutrition. ISSN 1549-7852