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Stereoselective synthesis towards (+)-trans-kumausyne employing vinylogous Mukaiyama type reaction on an α-chloro sulfide

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Title Stereoselective synthesis towards (+)-trans-kumausyne employing vinylogous Mukaiyama type reaction on an α-chloro sulfide
 
Creator Chowhan, L Raju
Raghavan, Sadagopan
 
Subject α-Chloro sulfide
Mukaiyama type reaction
Oxa-Michael addition
(+)-trans-Kumausyne
2-trimethylsiloxy furan
 
Description 1199-1205
A stereoselective synthesis towards (+)-trans-kumausyne is disclosed. The key steps of the synthesis include stereoselective C-C formation employing vinylogous Mukaiyama type reaction of an α-chloro sulfide with 2-trimethylsiloxy furan and base-catalyzed isomerization followed by intramolecular oxa-Michael reaction.
 
Date 2020-10-05T08:55:57Z
2020-10-05T08:55:57Z
2020-08
 
Type Article
 
Identifier 0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/55437
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJC-B Vol.59B(08) [August 2020]