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Synthesis and biological evaluation of novel indolyl-dihydropyridin-3-carboxylate, dihydro[1,2,4]triazol[1,5]pyridin-3-carboxylate and carbohydrazide derivatives
NOPR - NISCAIR Online Periodicals Repository
View Archive Info| Field | Value | |
| Title |
Synthesis and biological evaluation of novel indolyl-dihydropyridin-3-carboxylate, dihydro[1,2,4]triazol[1,5]pyridin-3-carboxylate and carbohydrazide derivatives
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| Creator |
Walmik, Prabhaker
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| Subject |
Indole
Dihydropyridine Dihydro[1,2,4]triazol[1,5]pyridine Antimicrobial Antioxidant Antitubercular activity |
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| Description |
1191-1198
The present study anticipates the development of novel antioxidant, antimicrobial and antitubercular drugs by using the indole scaffold. Novel indole derivatives, (4a-c), (5a-c) and (6a-i) have been prepared. The structures of all these unknown compounds have been confirmed with the help of elemental analysis, IR, 1H & 13C NMR and mass spectral data. All these previously unknown synthesized compounds screened for their antioxidant, antimicrobial and antitubercular activities. Compound 5a exhibited good RSA 76.58 %, IC50 value |
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| Date |
2020-10-05T08:58:43Z
2020-10-05T08:58:43Z 2020-08 |
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| Type |
Article
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| Identifier |
0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/55438 |
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| Language |
en_US
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| Rights |
 CC Attribution-Noncommercial-No Derivative Works 2.5 India
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| Publisher |
NISCAIR-CSIR, India
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| Source |
IJC-B Vol.59B(08) [August 2020]
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