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Synthesis and interaction of thiazolo [2, 3-a] isoquinoline analog with DNA

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Authentication Code dc
 
Title Statement Synthesis and interaction of thiazolo [2, 3-a] isoquinoline analog with DNA
 
Added Entry - Uncontrolled Name RANADE, PRASANNA B; Department of Chemistry, Vivekanand Education Society’s College of Arts, Science and Commerce, Sindhi Society, Chembur, Mumbai 400 071 INDIA.
Navale, Dinesh N; Department of Chemistry, Vivekanand Education Society’s College of Arts, Science and Commerce, Sindhi Society, Chembur, Mumbai 400 071 INDIA.
Zote, Santosh W; Department of Chemistry, Sathaye College Vile Parle (E), Mumbai 400 057
Ramana, M M V ; Department of Chemistry, University of Mumbai, Vidyanagari, Santacruz (E), Mumbai 400 098, INDIA.
FIST-DST Ministry of Science and Technology Govt. of INDIA and DBT STAR college scheme.
 
Uncontrolled Index Term DCC, Fluorescence, Static Quenching, Circular Dichroism.
 
Summary, etc. <p>A reaction between 1-(furan-2-yl)-3,4-dihydroisoquinoline and thioglycolic acid using DCC at 0<sup>0</sup>-5<sup>0</sup>C will give 10b-(furan-2-yl)-5,6-dihydro-2H-thiazolo[2,3-a]isoquinolin-3(10bH)-one [FUIQTGA]. The interaction between FUIQTGA and DNA was studied using UV Visible spectroscopy, fluorescence and Circular Dichroism (CD) techniques. Static quenching mechanism was observed from fluorescence measurements of interaction between FUIQTGA and DNA.  Circular Dichroism reveals the minor groove binding mode between FUIQTGA and DNA.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section A (IJCA)
2020-10-05 15:13:58
 
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http://op.niscair.res.in/index.php/IJCA/article/view/28558
 
Data Source Entry Indian Journal of Chemistry -Section A (IJCA); ##issue.vol## 59, ##issue.no## 4 (2020): INDIAN JOURNAL OF CHEMISTRY- SECTION A
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJCA/article/download/28558/465488055
http://op.niscair.res.in/index.php/IJCA/article/download/28558/465496014
 
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